In-Vitro Assessment of Synthesized Hydroxyapatite Specimen in Simulated Body Fluid (SBF)
Istikamah Subuki1, Ainina Kamarulzaman2, Nor Fadhreen Mohd Dahlan3

1Istikamah Subuki*, Faculty, Department of Chemical Engineering, University Technology MARA, Shah Alam, Selangor, Malaysia.
2Ainina Kamarulzaman, Faculty, Department of Chemical Engineering, University Technology MARA, Shah Alam, Selangor, Malaysia.
3Nor Fadhreen Mohd Dahlan, Faculty, Department of Chemical Engineering, University Technology MARA, Shah Alam, Selangor, Malaysia.
Manuscript received on January 13, 2020. | Revised Manuscript received on January 23, 2020. | Manuscript published on February 10, 2020. | PP: 2782-2786 | Volume-9 Issue-4, February 2020. | Retrieval Number: D2084029420/2020©BEIESP | DOI: 10.35940/ijitee.D2084.029420
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Abstract: Recently, the patient that requires bone replacement has increase, especially the patients who suffering from bone cancer, trauma and ageing. This attracts attention of researchers related to biomaterial fields to synthesis materials from biomaterials waste for bone tissue replacements. Hydroxyapatite was identified as a suitable source for bone substitution due its excellent bioactivity and biocompatibility. The strategies for tissue engineering include developing those cells to form the required tissue/organ in-vitro before inserting them into the body. This study is aimed to investigate In-Vitro properties of hydroxyapatite (HAp) specimens synthesize from the clamshells via precipitation method. HAp moulded specimen were immersed in the simulated body fluid (SBF). It displayed that the development of apatite layers materialized in the surface of HAp after being immersed for 25 days in the 1.5SBF. 
Keywords: Hydroxyapatite, Clamshell, In-Vitro, Simulated Body Fluids (SBF)
Scope of the Article: Fluid Mechanics