5924626f19493a390957d33 20250125063422933 beie:beie director@blueeyesintelligence.org WEB-FORM International Journal of Innovative Technology and Exploring Engineering IJITEE 22783075 10.35940/ijitee https://www.ijitee.org/ 01 30 2025 14 2 General Electric Healthcare Istanbul, Turkey. Dr. Aziz Ilyas OZTURK https://orcid.org/0000-0003-2350-5880 Prof. Dr. Osman YILDIRIM https://orcid.org/0000-0002-8900-3050 Istanbul Aydin University, Faculty of Engineering, Department of Electrical and Electronics Engineering, Istanbul, Turkey. Dr. Onur Deryahanoglu General Electric Healthcare Istanbul, Turkey. This study focuses on the segmentation and characterization of arachnoid cysts in brain MRI images, aiming to enhance diagnostic accuracy through advanced image processing techniques. Arachnoid cysts are cerebrospinal fluid-filled sacs located between the brain or spinal cord and the arachnoid membrane. These cysts can be asymptomatic but may also cause neurological symptoms such as headaches, seizures, or cognitive impairments when they increase in size or pressure. Accurate detection and characterization are essential for timely intervention and treatment. In this research, 269 brain MRI images were analyzed using connected component analysis (CCA) and contrast-limited adaptive histogram equalization (CLAHE). CLAHE was employed to enhance image contrast, particularly in regions with subtle intensity differences, while CCA facilitated the segmentation of connected regions corresponding to cysts. The smallest connected components were identified and analyzed to isolate arachnoid cysts with high precision. Post-segmentation, quantitative analysis was performed to extract features such as size, shape, and density, enabling comprehensive cyst characterization. Additionally, calculations for area and approximate volume were conducted, providing critical information for clinical assessment. Visual validation of segmentation outcomes confirmed the effectiveness of the applied methods in accurately delineating cyst boundaries. This research addresses a significant gap in the existing literature. While most studies focus on brain tumor segmentation, there is limited work on arachnoid cyst detection and volume estimation. By integrating image processing techniques tailored for arachnoid cysts, this study offers a novel approach to their diagnosis and monitoring. The findings demonstrate the potential for automated diagnostic tools, reducing subjectivity and improving efficiency in clinical workflows. The proposed methodology aligns with advancements in medical imaging and contributes to the development of improved tools for neuroimaging diagnostics, paving the way for more precise and reliable assessments in the detection of brain pathologies. 01 30 2025 01 30 2025 5 11 CC-BY-NC-ND 4.0 10.35940/BEIESP.CrossMarkPolicy www.ijitee.org true International Journal of Innovative Technology and Exploring Engineering (IJITEE) Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP) Based on my understanding, this article has no conflicts of interest. This article has not been sponsored or funded by any organization or agency. The independence of this research is a crucial factor in affirming its impartiality, as it has been conducted without any external sway. The data provided in this article is exempt from the requirement for ethical approval or participant consent. The adequate resources of this article are publicly accessible. The authorship of this article is contributed equally to all participating individuals. 10.35940/ijitee.B1031.14020125 https://www.ijitee.org/portfolio-item/B103114020125/