Wistar Rat Weight Loss on Conventional Cigarette Exposure Compared to E-Cigarette
Cakrawati Hanna1, Nurpangestu Budian2

1Cakrawati Hanna, Department of Physiology, Muhammadiyah University of Malang, Malang City, Indonesia. 

2Nurpangestu Budian, Medical School, Muhammadiyah University of Malang, Malang City, Indonesia. 

Manuscript received on 11 January 2020 | Revised Manuscript received on 07 February 2020 | Manuscript Published on 20 February 2020 | PP: 279-281 | Volume-9 Issue-3S January 2020 | Retrieval Number: C10640193S20/2020©BEIESP | DOI: 10.35940/ijitee.C1064.0193S20

Open Access | Editorial and Publishing Policies | Cite | Zenodo | Indexing and Abstracting
© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Abstract: Several studies have shown that smoking behavior is closely related to weight and obesity. Smokers tend to prefer fatty foods with high calories which ultimately makes a smoker vulnerable to being overweight. However, there are some studies that show lower body weight was found in smokers than nonsmokers. Our aim is to evaluate the short-term effects of smoking with conventional cigarettes and e-cigarret on weight changes in Wistar rats because animals try to minimize some confounding factors that are difficult to work on human samples (for example, physical activity, diet and motivation). This research is an experimental study, using 8-week-old male Wistar rats with body weight 150-200 grams divided randomly into 5 groups, namely 1) the group was not treated, 2) the filter cigarette exposure group, 3) the clove cigarette group , 4) e-cigarette group with a dose of 3 mL with nicotine content of 0 mg, and 5) ecigarette group with a dose of 3 mL with nicotine content of 3 mg. Body weight measurements using a digital scale. The results showed that there was a significant change in body weight between clove cigarettes and filter cigarettes with p = 0.024. In the results of this study, showed weight loss in all groups given cigarette smoke. Weight loss was significantly lower in the filter cigarette group compared to clove cigarettes and there was no significant weight difference between the conventional cigarette group and e-cigarette. This is likely the cigarette filter actually creates a major problem for smokers because of the design and materials used so it does not provide a safer effect for smoker.

Keywords: Cigarette, E-cigarette, Filter Cigarettes, Nicotine, Weight.
Scope of the Article: Social Sciences