Estimation of Cholesterol in the Presence of Urea and Other Constituents in Blood Tissue
Ingrid Anne Nazareth1, Jivan Parab2, Rajendra Gad3, Gourish Naik4

1Ingrid Anne Nazareth*, Assistant Prof., Dept. of Electronics, Taleigao Plateau, GU, Goa.
2Jivan Parab, Assistant Prof., Dept. of Electronics, Taleigao Plateau, GU, Goa,, Rajendra Gad, Prof. and Head, Dept. of Electronics, Taleigao Plateau, GU, Goa.
3Gourish Naik, Prof. (HAG) and Dean, Dept. of Electronics and Faculty of Natural Sciences, Taleigao Plateau, GU, Goa.
Manuscript received on December 12, 2019. | Revised Manuscript received on December 23, 2019. | Manuscript published on January 10, 2020. | PP: 1831-1834 | Volume-9 Issue-3, January 2020. | Retrieval Number: C8596019320/2020©BEIESP | DOI: 10.35940/ijitee.C8596.019320
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Abstract: The determination of cholesterol in pathological laboratories is more painful and may lead to infections if no proper precautions are taken into consideration. The manuscript presented here describes a non-invasive method to estimate blood cholesterol using Radio Frequency (RF) probe signal in the range of 10MHz – 500MHz. The method uses Scalar Network Analyzer and injects RF signal less than -30dbm, which is quite safe for human tissue and the frequency range falls in non-ionizing radiation wavelengths. Due to the absorption of RF signal by various body tissues including cholesterol, the received signal by the spectrum analyzer bears the signatures of percentage of the cholesterol present in the blood. These signatures are then analyzed using multivariate approach to estimate the Cholesterol. The Signal Processing Unit consists of Partial Least Square Regression (PLSR) tool based on the SIMPLS Algorithm. The results show that there is a good agreement between the predicted percentages of Cholesterol as compared to the actual. Though the study here uses only 5 components, the technique can also be used to include other blood components for the estimation of Cholesterol. 
Keywords:  RF Probe signal, PLSR, Signal Processing, Multivariate system.
Scope of the Article: Bio-science and Bio-technology