Synthesis of β-Amino Carbonyl Compounds via Mannich Reaction using Sulfated MCM-41
Pullar Vadivel1, Cinnathambi Subramani Maheswari2, Appaswami Lalitha3
1P. Vadivel, Department of Chemistry, Salem Sowdeswari College, Salem (Tamil Nadu), India.
2C. S. Maheswari , Department of Chemistry, Periyar University, Salem (Tamil Nadu), India.
3Dr. Appaswami Lalitha, Department of Chemistry, Periyar University, Salem (Tamil Nadu), India.
Manuscript received on 15 April 2013 | Revised Manuscript received on 22 April 2013 | Manuscript Published on 30 April 2013 | PP: 267-270 | Volume-2 Issue-5, April 2013 | Retrieval Number: E0712042413/13©BEIESP
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: One-pot three-component reaction of anilines with ketone and aldehyde leads to the formation of β-amino carbonyl compounds in the presence of sulfated MCM-41 as a recyclable solid acid catalyst. This method has several advantages like simple and easy work-up procedures with shorter reaction time and high yields of Mannich products.
Keywords: Β-Amino Carbonyl Compounds, Sulfated MCM- 41, Solid Acid Catalyst, Mannich Products.
Scope of the Article: Bio-Science and Bio-Technology